The acetylenic monoamine oxidase inhibitors clorgyline, deprenyl, pargyline and J‐508: their properties and applications
Identifieur interne : 002B41 ( Main/Exploration ); précédent : 002B40; suivant : 002B42The acetylenic monoamine oxidase inhibitors clorgyline, deprenyl, pargyline and J‐508: their properties and applications
Auteurs : C. J. Fowler [Irlande (pays)] ; L. Oreland [Suède] ; B. A. Callingham [Royaume-Uni]Source :
- Journal of Pharmacy and Pharmacology [ 0022-3573 ] ; 1981-09.
Abstract
The article presents a short review of some of the properties of the acetylenic inhibitors of monoamine oxidase currently under investigation: clorgyline, (—)‐deprenyl, pargyline and J‐508. Their substrate‐selective inactivation, mechanism of inhibition, titration and pharmacology with respect to monoamine oxidase are critically discussed.
Url:
DOI: 10.1111/j.2042-7158.1981.tb13800.x
Affiliations:
- Irlande (pays), Royaume-Uni, Suède
- Angleterre, Angleterre de l'Est
- Cambridge
- Université de Cambridge
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